Rubyat Hasan Chowdhury
BIRDEM General Hospital, Bangladesh.
Title: Non-Cardiac Causes of Raised Troponin-I in Adult Patients Admitted Under Cardiology Department in a Tertiary Level Hospital
Biography
Biography: Rubyat Hasan Chowdhury
Abstract
Objective: To find out different causes of raised troponin I in adult patients other than cardiac cause. Methodology: This cross sectional study was carried out enrolling 65 subjects with raised troponin I, in the Department of Cardiology, BIRDEM, Dhaka, over a period of six months from July 2013 to December 2013. Results: Most common non-cardiac cause of raised troponin I were sepsis (38.46%), CKD (32.3%), stroke (15.38%) and defibrillation (13.86%) in this present study. The mean age was 50.92 ± SD 12.77 years and their age ranged from 35 to 66 years. Majority (44.61%) of the respondents were found in the age group of 51-59 years. Gender distribution revealed that 40 (61.54%) were male and rests 25 (38.46%) were female . Hypertension (46.15%), dyslipidaemia (36.92%), diabetes mellitus (20%) and smoking (40%) were pre-existing risk factors in the study group. Chest pain (58.46%), breathlessness (46.15%), raised temperature (38.46%) and focal neurological deficit (15.38%) were the common presenting symptoms. X- ray revealed, cardiomagaly (9%) and pulmonary oedema (39%). Old infarct (12.3%), LV hypertrophy (43.07%) and arrhythmia (21.53%) were evident in ECG. Majority (52.3%) of the subjects had ≥60% LV dysfunction on Echocardiography. 18.46% had 50-59% LV dysfunction. 6.17 percent subjects had less than 30 % LV dysfunction. Conclusion: From the study result it can be concluded that subjects with sepsis, CKD, stroke and post-defibrillation are the commonly encountered with raised troponin I in cardiology wards other than ACS. As such, it could be noted that in case of patients with raised troponin I, these common condition should be excluded to avoid unnecessary treatment of ACS in subjects with raised troponin I.